Browsing Doctoral Theses by Author "Abdelhakim, Aliaa H. (Aliaa Hamid)"

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Auto-tethering as a selection mechanism for recognition of multimeric substrates by the AAA+ unfoldase ClpX

Abdelhakim, Aliaa H. (Aliaa Hamid) (Massachusetts Institute of Technology, 2008)

The CIp/Hsp1OO enzymes, which belong to the AAA+ family of ATPases, use their unfoldase activity to degrade and remodel multimeric substrates in the bacterial cell. The mechanical energy exerted by CIp/Hsp1OO enzymes drives ...