Browsing MIT Open Access Articles by Author "1000 Genomes Project Consortium"

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    • The landscape of human STR variation 

      Willems, Thomas Frederick; Gymrek, Melissa A.; Highnam, Gareth; 1000 Genomes Project Consortium; Mittelman, David; e.a. (Cold Spring Harbor Laboratory Press, 2014-08)
      Short tandem repeats are among the most polymorphic loci in the human genome. These loci play a role in the etiology of a range of genetic diseases and have been frequently utilized in forensics, population genetics, and ...

    • Mining data from 1000 genomes to identify the causal variant in regions under positive selection 

      Grossman, Sharon Rachel; Karlsson, Elinor K.; Tabrizi, Shervin; Andersen, Kristian G.; Rinn, John L.; e.a. (BioMed Central Ltd., 2010-10)
      The human genome contains hundreds of regions in which the patterns of genetic variation indicate recent positive natural selection, yet for most of these the underlying gene and the advantageous mutation remain unknown. ...