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dc.contributor.authorYannas, Ioannisen_US
dc.contributor.authorSpector, Myronen_US
dc.coverage.temporalFall 2003en_US
dc.date.issued2003-12
dc.identifier20.441-Fall2003
dc.identifierlocal: 20.441
dc.identifierlocal: 2.79J
dc.identifierlocal: 3.96J
dc.identifierlocal: HST.522J
dc.identifierlocal: IMSCP-MD5-e1af5d3c45e1048ac71d66822814879f
dc.identifier.urihttp://hdl.handle.net/1721.1/67471
dc.description.abstractThis course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Also addressed are criteria for restoration of physiological function for tissues and organs.en_US
dc.languageen-USen_US
dc.relationen_US
dc.rights.uriUsage Restrictions: This site (c) Massachusetts Institute of Technology 2011. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions.en_US
dc.subjectmedical implantsen_US
dc.subjectartificial organsen_US
dc.subjecttissue engineeringen_US
dc.subjectmatrixen_US
dc.subjectbiomaterialsen_US
dc.subjectprotein adsorptionen_US
dc.subjectunit cell processen_US
dc.subjectwound healingen_US
dc.subjecttissue remodelingen_US
dc.subjecttissue regenerationen_US
dc.subjectorgan regenerationen_US
dc.subjectprosthesisen_US
dc.subjectbiodegradableen_US
dc.subjectbioreplaceable implantsen_US
dc.subjectBE.441en_US
dc.subject2.79Jen_US
dc.subject3.96Jen_US
dc.subjectHST.522Jen_US
dc.subject2.79en_US
dc.subject3.96en_US
dc.subjectHST.522en_US
dc.title20.441 / 2.79J / 3.96J / HST.522J Biomaterials-Tissue Interactions (BE.441), Fall 2003en_US
dc.title.alternativeBiomaterials-Tissue Interactions (BE.441)en_US


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