This is an archived course. A more recent version may be available at ocw.mit.edu.

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Assignments

Homework 1 (PDF)

Homework 2 (PDF)

Homework 3 (PDF)

Notes for Homework 3: Consider both Phase 1 and Phase 2 reactions and come up with a reasonable number of possible metabolites, if you think there is more than one. You could explain the mechanism by:

  1. Name of the enzyme involved, and type of process (ex, HAT or SET), or
  2. Electron jumping showing the intermediates.

It is recommended to do both for some (but not all) reactions so that you will be well familiar with mechanisms covered in the class.

Homework 4 (PDF)

Notes for Homework 4: Identify the metabolites, and discuss their toxicity if there is any.

Homework 5 (PDF)