Browsing Chemical and Pharmaceutical Engineering (CPE) by Author "Stephanopoulos, Gregory"

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DNA Directed Assembly Probe for Detecting DNA-Protein Interaction in Microarray Format

Ng, Jin Kiat; Ajikumar, Parayil Kumaran; Tang, Yew Chung; Stephanopoulos, Gregory; Too, Heng-Phon (2007-01)

Quantifying DNA-protein interaction using DNA microarrays are gaining increasing attention due to their ability to profile specificity of interactions in a high-throughput manner. This paper describes a new approach that ...
Multivariate Perturbation of a Growth Factor-Cytokine Signalling Network Reveals Complex Systemic Responses in Glioblastoma Cells

Tang, Yew Chung; Wan, Guoqiang; Stephanopoulos, Gregory; Too, Heng-Phon (2007-01)

Glioblastoma cells can evade TRAIL-induced apoptosis through various strategies involving the growth factor-activated MEK–MAPK/ERK and PI3K–Akt/PKB pro-survival signalling cascades. Although these signalling cascades have ...