Browsing Chemical and Pharmaceutical Engineering (CPE) by Subject "Apoptosis"

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Multivariate Perturbation of a Growth Factor-Cytokine Signalling Network Reveals Complex Systemic Responses in Glioblastoma Cells

Tang, Yew Chung; Wan, Guoqiang; Stephanopoulos, Gregory; Too, Heng-Phon (2007-01)

Glioblastoma cells can evade TRAIL-induced apoptosis through various strategies involving the growth factor-activated MEK–MAPK/ERK and PI3K–Akt/PKB pro-survival signalling cascades. Although these signalling cascades have ...