Browsing Molecular Engineering of Biological and Chemical Systems (MEBCS) by Subject "aggregation"

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Molecular computations for reactions and phase transitions: applications to protein stabilization, hydrates and catalysis

Anderson, Brian J.; Baynes, Brian M.; Lo, Cynthia S.; Chu, Jhih-Wei; Pan, Bin; e.a. (2005-01)

In this work we have made significant contributions in three different areas of interest: therapeutic protein stabilization, thermodynamics of natural gas clathrate-hydrates, and zeolite catalysis. In all three fields, ...
Molecular Computations for the Stabilization of Therapeutic Proteins

Trout, Bernhardt L. (2004-01)

Molecular computations based on quantum mechanics and statistical mechanics have been applied to the understanding and quantification of processes leading to the degradation of therapeutic proteins. In particular, we focus ...
Stabilization of Proteins against Aggregation

Baynes, Brian M.; Wang, Daniel I.C.; Trout, Bernhardt L. (2004-01)

Proteins degrade in vitro by a variety of routes, the most common of which is aggregation. In order to develop protein formulations that will limit aggregation, researchers use heuristic, experimental screening procedures. ...